The Funny Bone Comedy Club has a reputation of being one of the most successful comedy clubs in the nation. That is due to the fact that some of the top comedians in the nation come to St. Louis to perform in the intimate setting that is one of the great appeals of the Funny Bone. There are two locations: Westport Plaza in Maryland Heights and Streets of St. Charles in St. Charles. Tickets can be purchased online or by calling the box office.