Archbishop John Glennon began building this beautiful cathedral in 1907 with a ground breaking ceremony and it wasn't offically completed until 1988. This "New Cathedral", as the locals call it, contains the largest mosaic collection in the world. Began in 1912 and completed in 1988, the mosaic collection was created by 20 different artists and covers 83,000 square feet and contains almost 42 million pieces of glass tesserae in more than 7,000 colors.

Visitors are encouraged to tour the cathedral on their own whenever there is not a mass or ceremony in progress. The cathedral also has a Mosaic Museum and the Cathedral Shop. The Cathedral Basilica hold special concerts and event throughout the year. Especially popular are the "Christmas at the Cathedral" concerts held during the Christmas season.

Daily Mass is held at the Cathedral Basilica, Monday through Friday, at 7am, 8am and 12:05pm. Saturday Mass is held at 8am and 5pm. Sunday Mass is held 4 times at 8am, 10am, 12pm and 5pm.